Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.
The amyloid cascade hypothesis of Alzheimer's disease (AD) is testable: it implies that interference with Abeta aggregation and plaque formation may be therapeutically useful. Abeta42 immunisation of amyloid precursor protein (APP) transgenic mice prevented plaque formation and caused removal o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2010-09.
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| Subjects: | |
| Online Access: | Get fulltext |