Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.
The amyloid cascade hypothesis of Alzheimer's disease (AD) is testable: it implies that interference with Abeta aggregation and plaque formation may be therapeutically useful. Abeta42 immunisation of amyloid precursor protein (APP) transgenic mice prevented plaque formation and caused removal o...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
2010-09.
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Subjects: | |
Online Access: | Get fulltext |