Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease

Hyperphosphorylation of the microtubule-associated protein tau is a significant determinant in AD (Alzheimer's disease), where it is associated with disrupted axonal transport and probably causes synaptic dysfunction. Although less well studied, hyperphosphorylation has been observed in prion d...

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Bibliographic Details
Main Authors: Asuni, Ayodeji A. (Author), Perry, V. Hugh (Author), O'Connor, Vincent (Author)
Format: Article
Language:English
Published: 2010-04.
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