Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease
Hyperphosphorylation of the microtubule-associated protein tau is a significant determinant in AD (Alzheimer's disease), where it is associated with disrupted axonal transport and probably causes synaptic dysfunction. Although less well studied, hyperphosphorylation has been observed in prion d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2010-04.
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| Subjects: | |
| Online Access: | Get fulltext |