Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

The tumor necrosis factor (TNF) superfamily protein TNF-like 1A (TL1A) is the ligand for death receptor 3 (DR3). TL1A is induced on activated dendritic cells (DCs) and its expression has been linked to human inflammatory bowel disease. To address how TL1A might influence intestinal inflammation, we...

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Bibliographic Details
Main Authors: Taraban, V. Y. (Author), Slebioda, T. J. (Author), Willoughby, J. E. (Author), Buchan, S. L. (Author), James, Sonya (Author), Sheth, B. (Author), Smyth, N. R. (Author), Thomas, G. J. (Author), Wang, E. C. Y. (Author), Al-Shamkhani, Aymen (Author)
Format: Article
Language:English
Published: 2011-03.
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