Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia
The tumor necrosis factor (TNF) superfamily protein TNF-like 1A (TL1A) is the ligand for death receptor 3 (DR3). TL1A is induced on activated dendritic cells (DCs) and its expression has been linked to human inflammatory bowel disease. To address how TL1A might influence intestinal inflammation, we...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2011-03.
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Subjects: | |
Online Access: | Get fulltext |