Association between APOE genotype, neuropathology and dementia in the older population of England and Wales

Aims: apolipoprotein E (APOE) genotype is the major genetic risk factor for sporadic Alzheimer's disease (AD) but it is unclear how this is mediated. Most studies of APOE genotype have used case-control design to compare groups differing by two variables: i.e. dementia and AD pathology, so it i...

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Bibliographic Details
Main Authors: Nicoll, J.A.R (Author), Savva, G.M (Author), Stewart, J. (Author), Matthews, F.E (Author), Brayne, C. (Author), Ince, P. (Author)
Format: Article
Language:English
Published: 2011-04.
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