Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

Maturation of neuronal synapses is thought to involve mitochondria. Bcl-xL protein inhibits mitochondria-mediated apoptosis but may have other functions in healthy adult neurons in which Bcl-xL is abundant. Here, we report that overexpression of Bcl-xL postsynaptically increases frequency and amplit...

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Main Authors: Li, Hongmei (Author), Chen, Yingbei (Author), Jones, Adrienne F. (Author), Sanger, Richard H. (Author), Collis, Leon P. (Author), Flannery, Richard (Author), McNay, Ewan C. (Author), Yu, Tingxi (Author), Schwarzenbacher, Robert (Author), Bossy, Blaise (Author), Bossy-Wetzel, Ella (Author), Bennett, Michael V.L (Author), Pypaert, Marc (Author), Hickman, John A. (Author), Smith, Peter J.S (Author), Hardwick, J. Marie (Author), Jonas, Elizabeth A. (Author)
Format: Article
Language:English
Published: 2008-02-12.
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