Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose

The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences. Glycolysis and mitochondrial metabolism both have key roles in the stimu...

Full description

Bibliographic Details
Main Authors: Heart, Emma (Author), Yaney, Gordon C. (Author), Corkey, Richard F. (Author), Schultz, Vera (Author), Luc, Esthere (Author), Liu, Lihan (Author), Deeney, Jude T. (Author), Shirihai, Orian (Author), Tornheim, Keith (Author), Smith, Peter J.S (Author), Corkey, Barbara E. (Author)
Format: Article
Language:English
Published: 2007-04-01.
Subjects:
Online Access:Get fulltext