Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia

Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia

Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct subgroup of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) that has a dismal outcome when treated with standard therapy. For improved diagnosis and risk stratification, the initiating genetic events need t...

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Bibliographic Details
Main Authors: Rand, Vikki (Author), Parker, Helen (Author), Russell, Lisa J (Author), Schwab, Claire (Author), Ensor, Hannah (Author), Irving, Julie (Author), Jones, Lisa (Author), Masic, Dino (Author), Minto, Lynne (Author), Morrison, Heather (Author), Ryan, Sarra (Author), Robinson, Hazel (Author), Sinclair, Paul (Author), Moorman, Anthony V (Author), Strefford, Jonathan C. (Author), Harrison, Christine J. (Author)
Format: Article
Language:English
Published: 2011-06-23.
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