HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes
HOXA10 is necessary for embryonic patterning of skeletal elements, but its function in bone formation beyond this early developmental stage is unknown. Here we show that HOXA10 contributes to osteogenic lineage determination through activation of Runx2 and directly regulates osteoblastic phenotypic...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2007-02-26.
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| Subjects: | |
| Online Access: | Get fulltext |