Structure of yeast 5-aminolaevulinic acid dehydratase complexed with the inhibitor 5-hydroxylaevulinic acid

The X-ray structure of the enzyme 5-aminolaevulinic acid dehydratase (ALAD) from yeast complexed with the competitive inhibitor 5-hydroxylaevulinic acid has been determined at a resolution of 1.9 Å . The structure shows that the inhibitor is bound by a Schiff-base link to one of the invariant activ...

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Main Authors: Erskine, P.T (Author), Coates, L. (Author), Newbold, R. (Author), Brindley, A.A (Author), Stauffer, F. (Author), Beaven, G.D.E (Author), Gill, R. (Author), Coker, A. (Author), Wood, S.P (Author), Warren, M.J (Author), Shoolingin-Jordan, P.M (Author), Neier, R. (Author), Cooper, J.B (Author)
Format: Article
Language:English
Published: 2005.
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