The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors
The structures of 5-aminolaevulinic acid dehydratase (ALAD) complexed with substrate (5-aminolaevulinic acid) and three inhibitors: laevulinic acid, succinylacetone and 4-keto-5-aminolaevulinic acid, have been solved at high resolution. The ligands all bind by forming a covalent link with Lys263 at...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2001-09.
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Subjects: | |
Online Access: | Get fulltext |