Influence of loop size on the stability of intramolecular DNA quadruplexes
We have determined the stability of intramolecular DNA quadruplexes in which the four G(3)-tracts are connected by non-nucleosidic linkers containing propanediol, octanediol or hexaethylene glycol, replacing the TTA loops in the human telomeric repeat sequence. We find that these sequences all fold...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
2004-05-11.
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Subjects: | |
Online Access: | Get fulltext |