The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

This report describes 2 patients with a clinical and hematologic diagnosis of chronic myeloid leukemia (CML) in chronic phase who had an acquired t(8;22)(p11;q11). Analysis by fluorescence in situ hybridization (FISH) and reverse transcription-polymerase chain reaction (RT-PCR) indicated that both p...

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Main Authors: Demiroglu, Asuman (Author), Steer, E. Joanna (Author), Heath, Carol (Author), Taylor, Kerry (Author), Bentley, Mark (Author), Allen, Steven L. (Author), Koduru, Prasad (Author), Brody, Judith P. (Author), Hawson, Geoffrey (Author), Rodwell, Robyn (Author), Doody, Mary Lou (Author), Carnicero, Fernando (Author), Reiter, Andreas (Author), Goldman, John M. (Author), Melo, Junia V. (Author), Cross, Nicholas C.P (Author)
Format: Article
Language:English
Published: 2001-12-15.
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