CD20-induced lymphoma cell death is independent of both caspases and its redistribution into Triton X-100 insoluble membrane rafts

Rituximab is routinely used for the treatment of neoplasia, although the mechanism of action remains uncertain. In the current study, CD20-induced apoptosis was investigated with a panel of anti-CD20 monoclonal antibodies (mAb) in a wide range of cell lines. A hierarchy of mAb activity was apparent,...

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Bibliographic Details
Main Authors: Chan, H.T. Claude (Author), Hughes, David (Author), French, Ruth R. (Author), Tutt, Alison L. (Author), Walshe, Claire A. (Author), Teeling, Jessica L. (Author), Glennie, Martin J. (Author), Cragg, Mark S. (Author)
Format: Article
Language:English
Published: 2003-09-01.
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