CD20-induced lymphoma cell death is independent of both caspases and its redistribution into Triton X-100 insoluble membrane rafts
Rituximab is routinely used for the treatment of neoplasia, although the mechanism of action remains uncertain. In the current study, CD20-induced apoptosis was investigated with a panel of anti-CD20 monoclonal antibodies (mAb) in a wide range of cell lines. A hierarchy of mAb activity was apparent,...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2003-09-01.
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Subjects: | |
Online Access: | Get fulltext |