Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

This study evaluates the prognostic significance of genetic abnormalities (detected at or shortly after presentation), clinical stage, lymphocyte morphology, CD38 expression, and IGVH gene status in 205 patients with chronic lymphocytic leukemia (B-CLL). Deletion of chromosome 11q23, absence of a de...

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Main Authors: Oscier, David G. (Author), Gardiner, Anne C. (Author), Mould, Sarah J. (Author), Glide, Sharron (Author), Davis, Zadie A. (Author), Ibbotson, Rachel E. (Author), Corcoran, Martin M. (Author), Chapman, Robert M. (Author), Thomas, Peter W. (Author), Copplestone, J. Adrian (Author), Orchard, Jenny A. (Author), Hamblin, Terry J. (Author)
Format: Article
Language:English
Published: 2002-08.
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