The mechanisms of regulation of Hdm2 protein level by serum growth factors
Cell cycle progression in response to serum growth factors is dependent on the expression of functional Hdm2 (Mdm2), which inhibits p53-dependent transcription of anti-proliferative genes. In a well characterised non-transformed human fibroblast model, growth factors induce the expression of Hdm2 wi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2006-01-09.
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| Subjects: | |
| Online Access: | Get fulltext |