Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events
There exists a wide spectrum of IgM-secreting B-cell tumors with different clinical behavior. Knowledge of the VH gene status can reveal their origin and clonal history. For Waldenstrom macroglobulinemia (WM), a distinct subtype of lymphoplasmacytic lymphoma, early data on limited sequences showed e...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2002-08-15.
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| Subjects: | |
| Online Access: | Get fulltext |