?-Melanocyte-stimulating hormone suppresses antigen-induced lymphocyte proliferation in humans independently of melanocortin 1 receptor gene status

Studies in mice indicate that ? -melanocyte-stimulating hormone (?MSH) is immunosuppressive, but it is not known whether ?MSH suppresses human immune responses to exogenous Ags. Human PBMCs, including monocytes, express the melanocortin 1 receptor (MC1R), and it is thought that the ability of ?MSH t...

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Bibliographic Details
Main Authors: Cooper, Ashley (Author), Robinson, Samantha J. (Author), Pickard, Chris (Author), Jackson, Claire L. (Author), Friedmann, Peter S. (Author), Healy, Eugene (Author)
Format: Article
Language:English
Published: 2005-10-01.
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