Biotransformation to nitric oxide of organic nitrates in comparison to other nitrovasodilators
Nitrovasodilators are prodrugs which, although chemically heterogenous, exert their pharmacodynamic action via a common pathway, i.e. the release of nitric oxide (NO). The NO, which results from metabolism of nitrovasodilators in vascular and non-vascular cells, stimulates the cytosolic enzyme guany...
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Format: | Article |
Language: | English |
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1993-11.
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Online Access: | Get fulltext |