Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring
These results demonstrate for the first time that the preimplantation embryo in vivo is sensitive to maternal systemic inflammation, with effects on blastocyst cell lineage allocation and consequences for behaviour, adiposity and innate immune response in adult offspring. Critically, we identify a n...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2011.
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| Subjects: | |
| Online Access: | Get fulltext |