Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction

Abstract In this study, we investigate the underlying mechanisms of antibody-mediated inflammation in the brain. We show that immune complexes formed in the brain parenchyma generate a robust and long-lasting inflammatory response, characterized by increased expression of the microglia markers CD11b...

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Bibliographic Details
Main Authors: Teeling, Jessica L. (Author), Carare, Roxana O. (Author), Glennie, Martin J. (Author), Perry, V. Hugh (Author)
Format: Article
Language:English
Published: 2012-10.
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