ROCS: a reproducibility index and confidence score for interaction proteomics

Affinity-Purification Mass-Spectrometry (AP-MS) provides a powerful means of identifying protein complexes and interactions. Several important challenges exist in interpreting the results of AP-MS experiments. First, the reproducibility of AP-MS experimental replicates can be low, due both to techni...

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Bibliographic Details
Main Authors: Dazard, Jean-Eudes J. (Author), Saha, Sudipto (Author), Ewing, Rob M. (Author)
Format: Article
Language:English
Published: 2012-06-08.
Subjects:
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