ROCS: a reproducibility index and confidence score for interaction proteomics
Affinity-Purification Mass-Spectrometry (AP-MS) provides a powerful means of identifying protein complexes and interactions. Several important challenges exist in interpreting the results of AP-MS experiments. First, the reproducibility of AP-MS experimental replicates can be low, due both to techni...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
2012-06-08.
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Subjects: | |
Online Access: | Get fulltext |