Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion. Analysis of mammalian NSF function during cell-free assembly of Golgi ciste...

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Main Authors: Müller, Joyce M.M (Author), Shorter, James (Author), Newman, Richard (Author), Deinhardt, Katrin (Author), Sagiv, Yuval (Author), Elazar, Zvulun (Author), Warren, Graham (Author), Shima, David T. (Author)
Format: Article
Language:English
Published: 2002-06-24.
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