Maternal TLR4 and NOD2 gene variants, pro-inflammatory phenotype and susceptibility to early-onset preeclampsia and HELLP syndrome

Maternal TLR4 and NOD2 gene variants, pro-inflammatory phenotype and susceptibility to early-onset preeclampsia and HELLP syndrome

Background: Altered maternal inflammatory responses play a role in the development of preeclampsia and the hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. We examined whether allelic variants of the innate immune receptors Toll-like receptor 4 (TLR4) and nucleotide-binding olig...

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Main Authors: van Rijn, Bas B. (Author), Franx, Arie (Author), Steegers, Eric A.P (Author), de Groot, Christianne J.M (Author), Bertina, Rogier M. (Author), Pasterkamp, Gerard (Author), Voorbij, Hieronymus A.M (Author), Bruinse, Hein W. (Author), Roest, Mark (Author)
Format: Article
Language:English
Published: 2008-04-02.
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