A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin ? C as a compatible prognostic marker in human solid tumors.

Our findings provide IGKC as a novel diagnostic marker for risk stratification in human cancer and support concepts to exploit the humoral immune response for anticancer therapy. It could be validated in several independent cohorts and carried out similarly well in RNA from fresh frozen as well as f...

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Main Authors: Schmidt, Marcus (Author), Hellwig, Birte (Author), Hammad, Seddik (Author), Othman, Amnah (Author), Lohr, Miriam (Author), Chen, Zonglin (Author), Boehm, Daniel (Author), Gebhard, Susanne (Author), Petry, Ilka (Author), Lebrecht, Antje (Author), Cadenas, Cristina (Author), Marchan, Rosemarie (Author), Stewart, Joanna D (Author), Solbach, Christine (Author), Holmberg, Lars (Author), Edlund, Karolina (Author), Kultima, Hanna Göransson (Author), Rody, Achim (Author), Berglund, Anders (Author), Lambe, Mats (Author), Isaksson, Anders (Author), Botling, Johan (Author), Karn, Thomas (Author), Müller, Volkmar (Author), Gerhold-Ay, Aslihan (Author), Cotarelo, Christina (Author), Sebastian, Martin (Author), Kronenwett, Ralf (Author), Bojar, Hans (Author), Lehr, Hans-Anton (Author), Sahin, Ugur (Author), Koelbl, Heinz (Author), Gehrmann, Mathias (Author), Micke, Patrick (Author), Rahnenführer, Jörg (Author), Hengstler, Jan G (Author)
Format: Article
Language:English
Published: 2012-05-01.
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