Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: Kinetic analysis of His263 and Ser110 site-directed mutants
C-C hydrolase MhpC (2-hydroxy-6-keto-nona-1,9-dioic acid 5,6-hydrolase) from Escherichia coli catalyses the hydrolytic C-C cleavage of the meta-ring fission product on the phenylpropionic acid catabolic pathway. The crystal structure of E. coli MhpC has revealed a number of active-site amino acid re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2005-02-01.
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| Subjects: | |
| Online Access: | Get fulltext |