The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling

Interleukin-4 (IL-4) and Interleukin-13 (IL-13), key cytokines in the pathogenesis of allergic inflammatory disease, mediate their effects via a receptor composed of IL-13R?1 and IL-4R?. A third (decoy) receptor called IL-13R?2 regulates interleukin signaling through this receptor complex. We employ...

Full description

Bibliographic Details
Main Authors: Andrews, Allison-Lynn (Author), Nordgren, Ida Karin (Author), Campbell-Harding, Gemma (Author), Holloway, John W. (Author), Holgate, Stephen T. (Author), Davies, Donna E. (Author), Tavassoli, Ali (Author)
Format: Article
Language:English
Published: 2013-12-01.
Subjects:
Online Access:Get fulltext