Single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers

Single-channel electrophysiology with lipid bilayer systems requires ion channel expression, purification from cell culture, and reconstitution in proteoliposomes for delivery to a planar bilayer. Here we demonstrate that single-channel current measurements of the potassium channels KcsA and hERGS5-...

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Bibliographic Details
Main Authors: Friddin, Mark S. (Author), Smithers, Natalie P. (Author), Beaugrand, Maïwenn (Author), Marcotte, Isabelle (Author), Williamson, Philip T.F (Author), Morgan, Hywel (Author), de Planque, Maurits R.R (Author)
Format: Article
Language:English
Published: 2013-10-18.
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