Triplex-mediated analysis of cytosine methylation at CpA sites in DNA
Modified triplex-forming oligonucleotides distinguish 5-methyl cytosine from unmethylated cytosine in DNA duplexes by differences in triplex melting temperatures. The discrimination is sequence-specific; dramatic differences in stabilisation are seen for CpA methylation, whereas CpG methylation is n...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014-01-18.
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| Subjects: | |
| Online Access: | Get fulltext |