Female and male gamete mitochondria are distinct and complementary in transcription, structure, and genome function

Respiratory electron transport in mitochondria is coupled to ATP synthesis while generating mutagenic oxygen free radicals. Mitochondrial DNA mutation then accumulates with age, and may set a limit to the lifespan of individual, multicellular organisms. Why is this mutation not inherited? Here we de...

Full description

Bibliographic Details
Main Authors: de Paula, Wilson B.M (Author), Agip, Ahmed-Noor A. (Author), Missirlis, Fanis (Author), Ashworth, Rachel (Author), Vizcay-Barrena, Gemma (Author), Lucas, Cathy H. (Author), Allen, John F (Author)
Format: Article
Language:English
Published: 2013.
Subjects:
Online Access:Get fulltext