Harnessing nanotopography and integrin-matrix interactions to influence stem cell fate

Stem cells respond to nanoscale surface features, with changes in cell growth and differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical features with integrin receptors in the cells' focal adhesions alters how the cells adhere to materials surfaces, and...

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Bibliographic Details
Main Authors: Dalby, Matthew J. (Author), Gadegaard, Nikolaj (Author), Oreffo, Richard O.C (Author)
Format: Article
Language:English
Published: 2014-05-21.
Subjects:
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