A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

Glaucoma is a major cause of blindness in the world. To date, common genetic variants associated with glaucoma only explain a small proportion of its heritability. We performed a genome-wide association study of intra-ocular pressure (IOP), an underlying endophenotype for glaucoma. The discovery pha...

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Main Authors: Nag, A. (Author), Venturini, C. (Author), Small, K.S (Author), Young, T. L. (Author), Viswanathan, A.C (Author), Mackey, D.A (Author), Hysi, P.G (Author), Hammond, C. (Author), Aung, T. (Author), Cheng, C.-Y (Author), Fleck, B.W (Author), Gibson, J. (Author), Hewitt, A.W (Author), Hofman, A. (Author), Hohn, R. (Author), Jonas, J.B (Author), Khor, C.-C (Author), Klaver, C.C (Author), Lemij, H.G (Author), Liao, J. (Author), Lotery, A.J (Author), Lu, Y. (Author), Macgregor, S. (Author), Mitchell, P. (Author), Ramdas, W.D (Author), Springelkamp, H. (Author), Tai, E.-S (Author), Teo, Y.-Y (Author), Uitterlinden, A.G (Author), van Duijn, C.M (Author), van Koolwijk, L.M (Author), Vingerling, J.R (Author), Vitart, V. (Author), Vithana, E. (Author), Wang, J.J (Author), Williams, K.M (Author), Wojciechowski, R. (Author), Wong, T.-Y (Author), WTCCC, None (Author), Xu, L. (Author), Yonova-Doing, E. (Author), Tanja, Z. (Author)
Format: Article
Language:English
Published: 2014-06-15.
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