Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We conducted a large, two-stage meta-analysis of genome-wide association studies (GWAS) in individuals of...

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Main Authors: Lambert, Jean-Charles (Author), Ibrahim-Verbaas, Carla A (Author), Harold, Denise (Author), Naj, Adam C (Author), Sims, Rebecca (Author), Bellenguez, Céline (Author), Jun, Gyungah (Author), DeStefano, Anita L (Author), Bis, Joshua C (Author), Beecham, Gary W (Author), Grenier-Boley, Benjamin (Author), Russo, Giancarlo (Author), Thornton-Wells, Tricia A (Author), Jones, Nicola (Author), Smith, Albert V (Author), Chouraki, Vincent (Author), Thomas, Charlene (Author), Ikram, M Arfan (Author), Zelenika, Diana (Author), Vardarajan, Badri N (Author), Kamatani, Yoichiro (Author), Lin, Chiao-Feng (Author), Gerrish, Amy (Author), Schmidt, Helena (Author), Kunkle, Brian (Author), Dunstan, Melanie L (Author), Ruiz, Agustin (Author), Bihoreau, Marie-Thérèse (Author), Choi, Seung-Hoan (Author), Reitz, Christiane (Author), Pasquier, Florence (Author), Hollingworth, Paul (Author), Ramirez, Alfredo (Author), Hanon, Olivier (Author), Fitzpatrick, Annette L (Author), Buxbaum, Joseph D (Author), Campion, Dominique (Author), Crane, Paul K (Author), Baldwin, Clinton (Author), Becker, Tim (Author), Gudnason, Vilmundur (Author), Cruchaga, Carlos (Author), Craig, David (Author), Amin, Najaf (Author), Berr, Claudine (Author), Lopez, Oscar L (Author), De Jager, Philip L (Author), Deramecourt, Vincent (Author), Johnston, Janet A (Author), Evans, Denis (Author), Lovestone, Simon (Author), Letenneur, Luc (Author), Morón, Francisco J (Author), Rubinsztein, David C (Author), Eiriksdottir, Gudny (Author), Sleegers, Kristel (Author), Goate, Alison M (Author), Fiévet, Nathalie (Author), Huentelman, Matthew J (Author), Gill, Michael (Author), Brown, Kristelle (Author), Kamboh, M Ilyas (Author), Keller, Lina (Author), Barberger-Gateau, Pascale (Author), McGuinness, Bernadette (Author), Larson, Eric B (Author), Green, Robert (Author), Myers, Amanda J (Author), Dufouil, Carole (Author), Todd, Stephen (Author), Wallon, David (Author), Love, Seth (Author), Rogaeva, Ekaterina (Author), Gallacher, John (Author), St George-Hyslop, Peter (Author), Clarimon, Jordi (Author), Lleo, Alberto (Author), Bayer, Anthony (Author), Tsuang, Debby W (Author), Yu, Lei (Author), Tsolaki, Magda (Author), Bossù, Paola (Author), Spalletta, Gianfranco (Author), Proitsi, Petroula (Author), Collinge, John (Author), Sorbi, Sandro (Author), Sanchez-Garcia, Florentino (Author), Fox, Nick C (Author), Hardy, John (Author), Naranjo, Maria Candida Deniz (Author), Bosco, Paolo (Author), Clarke, Robert (Author), Brayne, Carol (Author), Galimberti, Daniela (Author), Mancuso, Michelangelo (Author), Matthews, Fiona (Author), Moebus, Susanne (Author), Mecocci, Patrizia (Author), Del Zompo, Maria (Author), Maier, Wolfgang (Author), Hampel, Harald (Author), Pilotto, Alberto (Author), Bullido, Maria (Author), Panza, Francesco (Author), Caffarra, Paolo (Author), Nacmias, Benedetta (Author), Gilbert, John R (Author), Mayhaus, Manuel (Author), Lannfelt, Lars (Author), Hakonarson, Hakon (Author), Pichler, Sabrina (Author), Carrasquillo, Minerva M (Author), Ingelsson, Martin (Author), Beekly, Duane (Author), Alvarez, Victoria (Author), Zou, Fanggeng (Author), Valladares, Otto (Author), Younkin, Steven G (Author), Coto, Eliecer (Author), Hamilton-Nelson, Kara L (Author), Gu, Wei (Author), Razquin, Cristina (Author), Pastor, Pau (Author), Mateo, Ignacio (Author), Owen, Michael J (Author), Faber, Kelley M (Author), Jonsson, Palmi V (Author), Combarros, Onofre (Author), O'Donovan, Michael C (Author), Cantwell, Laura B (Author), Soininen, Hilkka (Author), Blacker, Deborah (Author), Mead, Simon (Author), Mosley, Thomas H (Author), Bennett, David A (Author), Harris, Tamara B (Author), Fratiglioni, Laura (Author), Holmes, Clive (Author), de Bruijn, Renee F A G (Author), Passmore, Peter (Author), Montine, Thomas J (Author), Bettens, Karolien (Author), Rotter, Jerome I (Author), Brice, Alexis (Author), Morgan, Kevin (Author), Foroud, Tatiana M (Author), Kukull, Walter A (Author), Hannequin, Didier (Author), Powell, John F (Author), Nalls, Michael A (Author), Ritchie, Karen (Author), Lunetta, Kathryn L (Author), Kauwe, John S K (Author), Boerwinkle, Eric (Author), Riemenschneider, Matthias (Author), Boada, Mercè (Author), Hiltunen, Mikko (Author), Martin, Eden R (Author), Schmidt, Reinhold (Author), Rujescu, Dan (Author), Wang, Li-San (Author), Dartigues, Jean-François (Author), Mayeux, Richard (Author), Tzourio, Christophe (Author), Hofman, Albert (Author), Nöthen, Markus M (Author), Graff, Caroline (Author), Psaty, Bruce M (Author), Jones, Lesley (Author), Haines, Jonathan L (Author), Holmans, Peter A (Author), Lathrop, Mark (Author), Pericak-Vance, Margaret A (Author), Launer, Lenore J (Author), Farrer, Lindsay A (Author), van Duijn, Cornelia M (Author), Van Broeckhoven, Christine (Author), Moskvina, Valentina (Author), Seshadri, Sudha (Author), Williams, Julie (Author), Schellenberg, Gerard D (Author), Amouyel, Philippe (Author)
Format: Article
Language:English
Published: 2013.
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