Cancer associated fibroblasts predict for poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

Cancer associated fibroblasts predict for poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

Interactions between cancer cells and cancer-associated fibroblasts (CAF) play an important role in tumour development and progression. In this study we investigated the functional role of CAF in oesophageal adenocarcinoma (EAC). We used immunochemistry to analyse a cohort of EAC patients (183 patie...

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Main Authors: Underwood, Timothy J. (Author), Hayden, Annette L. (Author), Derouet, Mathieu (Author), Garcia, Edwin (Author), Noble, Fergus (Author), White, Michael J. (Author), Thirdborough, Steve (Author), Mead, Abbie (Author), Clemons, Nicholas (Author), Mellone, Massimiliano (Author), Uzoho, Chudy (Author), Primrose, John N (Author), Blaydes, Jeremy P (Author), Thomas, Gareth J (Author)
Format: Article
Language:English
Published: 2015-01.
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