Screening ion-channel ligand interactions with passive pumping in a microfluidic bilayer lipid membrane (BLM) chip

We describe a scalable artificial bilayer lipid membrane (BLM) platform for rapid electrophysiological screening of ion channels and transporters. A passive pumping method is used to flow microliter volumes of ligand solution across a suspended bilayer within a microfluidic chip. Bilayers are stable...

Full description

Bibliographic Details
Main Authors: Saha, Shimul C. (Author), Powl, Andrew M. (Author), Wallace, B. A. (Author), de Planque, Maurits R.R (Author), Morgan, Hywel (Author)
Format: Article
Language:English
Published: 2015-01-09.
Subjects:
Online Access:Get fulltext