The extracellular matrix regulates granuloma necrosis in tuberculosis
A central tenet of tuberculosis (TB) pathogenesis is that caseous necrosis leads to extracellular matrix destruction and bacterial transmission. We reconsider the underlying mechanism of TB pathology and demonstrate that collagen destruction may be a critical initial event, causing caseous necrosis...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2015-08-01.
|
| Subjects: | |
| Online Access: | Get fulltext |