Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite
The c-Jun N-terminal protein kinase (JNK)/c-jun and p53 pathways form distinct death-signaling modules in neurons that culminate in Bax-dependent apoptosis. To investigate whether this signaling autonomy is due to recruitment of particular BH3-only proteins, we searched for a toxic signal that would...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2005-10.
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| Subjects: | |
| Online Access: | Get fulltext |