Viral infection of human lung macrophages increases PDL1 expression via IFNβ

Viral infection of human lung macrophages increases PDL1 expression via IFNβ

Lung macrophages are an important defence against respiratory viral infection and recent work has demonstrated that influenza-induced macrophage PDL1 expression in the murine lung leads to rapid modulation of CD8+ T cell responses via the PD1 receptor. This PD1/PDL1 pathway may downregulate acute in...

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Main Authors: Staples, Karl J. (Author), Nicholas, Ben (Author), McKendry, Richard T. (Author), Spalluto, C. Mirella (Author), Wallington, Joshua C. (Author), Bragg, Craig W. (Author), Robinson, Emily C. (Author), Martin, Kirstin (Author), Djukanović, Ratko (Author), Wilkinson, Tom M.A (Author)
Format: Article
Language:English
Published: 2015-03-16.
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