Folic acid supplementation in vitro induces cell type-specific changes in BRCA1 and BRCA 2 mRNA Expression, but does not alter DNA methylation of their promoters or DNA repair
Dietary supplementation with folic acid (FA) has been shown to induce opposing effects on cancer-related outcomes. The mechanism underlying such heterogeneity is unclear. We hypothesized that FA supplementation induces changes in breast cancer-associated (BRCA) genes 1 and 2 expression and function...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015-04-18.
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| Subjects: | |
| Online Access: | Get fulltext |