Identification of six new susceptibility loci for invasive epithelial ovarian cancer

Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After imputation to 1000 Genomes Project data, we assessed associ...

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Main Authors: Kuchenbaecker, Karoline B. (Author), Ramus, Susan J. (Author), Tyrer, Jonathan (Author), Lee, Andrew (Author), Shen, Howard C. (Author), Beesley, Jonathan (Author), Lawrenson, Kate (Author), McGuffog, Lesley (Author), Healey, Sue (Author), Lee, Janet M. (Author), Spindler, Tassja J. (Author), Lin, Yvonne G. (Author), Pejovic, Tanja (Author), Bean, Yukie (Author), Li, Qiyuan (Author), Coetzee, Simon (Author), Hazelett, Dennis (Author), Miron, Alexander (Author), Southey, Melissa (Author), Terry, Mary Beth (Author), Goldgar, David E. (Author), Buys, Saundra S. (Author), Janavicius, Ramunas (Author), Dorfling, Cecilia M. (Author), van Rensburg, Elizabeth J. (Author), Neuhausen, Susan L. (Author), Ding, Yuan Chun (Author), Hansen, Thomas V.O (Author), Jønson, Lars (Author), Gerdes, Anne-Marie (Author), Ejlertsen, Bent (Author), Barrowdale, Daniel (Author), Dennis, Joe (Author), Benitez, Javier (Author), Osorio, Ana (Author), Garcia, Maria Jose (Author), Komenaka, Ian (Author), Weitzel, Jeffrey N. (Author), Ganschow, Pamela (Author), Peterlongo, Paolo (Author), Bernard, Loris (Author), Viel, Alessandra (Author), Bonanni, Bernardo (Author), Peissel, Bernard (Author), Manoukian, Siranoush (Author), Radice, Paolo (Author), Papi, Laura (Author), Ottini, Laura (Author), Fostira, Florentia (Author), Konstantopoulou, Irene (Author), Garber, Judy (Author), Frost, Debra (Author), Perkins, Jo (Author), Platte, Radka (Author), Ellis, Steve (Author), Godwin, Andrew K (Author), Schmutzler, Rita Katharina (Author), Meindl, Alfons (Author), Engel, Christoph (Author), Sutter, Christian (Author), Sinilnikova, Olga M (Author), Damiola, Francesca (Author), Mazoyer, Sylvie (Author), Stoppa-Lyonnet, Dominique (Author), Claes, Kathleen (Author), De Leeneer, Kim (Author), Kirk, Judy (Author), Rodriguez, Gustavo C. (Author), Piedmonte, Marion (Author), O'Malley, David M. (Author), de la Hoya, Miguel (Author), Caldes, Trinidad (Author), Aittomäki, Kristiina (Author), Nevanlinna, Heli (Author), Collée, J. Margriet (Author), Rookus, Matti A. (Author), Oosterwijk, Jan C. (Author), Tihomirova, Laima (Author), Tung, Nadine (Author), Hamann, Ute (Author), Isaccs, Claudine (Author), Tischkowitz, Marc (Author), Imyanitov, Evgeny N. (Author), Caligo, Maria A. (Author), Campbell, Ian G. (Author), Hogervorst, Frans B.L (Author), Olah, Edith (Author), Diez, Orland (Author), Blanco, Ignacio (Author), Brunet, Joan (Author), Lazaro, Conxi (Author), Pujana, Miquel Angel (Author), Jakubowska, Anna (Author), Gronwald, Jacek (Author), Lubinski, Jan (Author), Sukiennicki, Grzegorz (Author), Barkardottir, Rosa B (Author), Plante, Marie (Author), Simard, Jacques (Author), Soucy, Penny (Author), Montagna, Marco (Author), Tognazzo, Silvia (Author), Teixeira, Manuel R. (Author), Pankratz, Vernon S. (Author), Wang, Xianshu (Author), Lindor, Noralane (Author), Szabo, Csilla I. (Author), Kauff, Noah (Author), Vijai, Joseph (Author), Aghajanian, Carol A. (Author), Pfeiler, Georg (Author), Berger, Andreas (Author), Singer, Christian F. (Author), Tea, Muy-Kheng (Author), Phelan, Catherine M. (Author), Greene, Mark H. (Author), Mai, Phuong L. (Author), Rennert, Gad (Author), Mulligan, Anna Marie (Author), Tchatchou, Sandrine (Author), Andrulis, Irene L. (Author), Glendon, Gord (Author), Toland, Amanda Ewart (Author), Jensen, Uffe Birk (Author), Kruse, Torben A. (Author), Thomassen, Mads (Author), Bojesen, Anders (Author), Zidan, Jamal (Author), Friedman, Eitan (Author), Laitman, Yael (Author), Soller, Maria (Author), Liljegren, Annelie (Author), Arver, Brita (Author), Einbeigi, Zakaria (Author), Stenmark-Askmalm, Marie (Author), Olopade, Olufunmilayo I. (Author), Nussbaum, Robert L. (Author), Rebbeck, Timothy R (Author), Nathanson, Katherine L. (Author), Domchek, Susan M. (Author), Lu, Karen H. (Author), Karlan, Beth Y. (Author), Walsh, Christine (Author), Lester, Jenny (Author), Hein, Alexander (Author), Ekici, Arif B. (Author), Beckmann, Matthias W. (Author), Fasching, Peter A. (Author), Lambrechts, Diether (Author), Van Nieuwenhuysen, Els (Author), Vergote, Ignace (Author), Lambrechts, Sandrina (Author), Dicks, Ed (Author), Doherty, Jennifer A. (Author), Wicklund, Kristine G. (Author), Rossing, Mary Anne (Author), Rudolph, Anja (Author), Chang-Claude, Jenny (Author), Wang-Gohrke, Shan (Author), Eilber, Ursula (Author), Moysich, Kirsten B. (Author), Odunsi, Kunle (Author), Sucheston, Lara (Author), Lele, Shashi (Author), Wilkens, Lynne R. (Author), Goodman, Marc T. (Author), Thompson, Pamela J. (Author), Shvetsov, Yurii B. (Author), Runnebaum, Ingo B. (Author), Dürst, Matthias (Author), Hillemanns, Peter (Author), Dörk, Thilo (Author), Antonenkova, Natalia (Author), Bogdanova, Natalia (Author), Leminen, Arto (Author), Pelttari, Liisa M. (Author), Butzow, Ralf (Author), Modugno, Francesmary (Author), Kelley, Joseph L. (Author), Edwards, Robert P. (Author), Ness, Roberta B. (Author), du Bois, Andreas (Author), Heitz, Florian (Author), Schwaab, Ira (Author), Harter, Philipp (Author), Matsuo, Keitaro (Author), Hosono, Satoyo (Author), Orsulic, Sandra (Author), Jensen, Allan (Author), Kjaer, Susanne Kruger (Author), Hogdall, Estrid (Author), Hasmad, Hanis Nazihah (Author), Azmi, Mat Adenan Noor (Author), Teo, Soo-Hwang (Author), Woo, Yin-Ling (Author), Fridley, Brooke L. (Author), Goode, Ellen L. (Author), Cunningham, Julie M. (Author), Vierkant, Robert A. (Author), Bruinsma, Fiona (Author), Giles, Graham G. (Author), Liang, Dong (Author), Hildebrandt, Michelle A.T (Author), Wu, Xifeng (Author), Levine, Douglas A. (Author), Bisogna, Maria (Author), Berchuck, Andrew (Author), Iversen, Edwin S. (Author), Schildkraut, Joellen M. (Author), Concannon, Patrick (Author), Weber, Rachel Palmieri (Author), Cramer, Daniel W. (Author), Terry, Kathryn L. (Author), Poole, Elizabeth M. (Author), Tworoger, Shelley S. (Author), Bandera, Elisa V. (Author), Orlow, Irene (Author), Olson, Sara H. (Author), Krakstad, Camilla (Author), Salvesen, Helga B. (Author), Tangen, Ingvild L. (Author), Bjorge, Line (Author), van Altena, Anne M. (Author), Aben, Katja K.H (Author), Kiemeney, Lambertus A. (Author), Massuger, Leon F.A.G (Author), Kellar, Melissa (Author), Brooks-Wilson, Angela (Author), Kelemen, Linda E. (Author), Cook, Linda S. (Author), Le, Nhu D. (Author), Cybulski, Cezary (Author), Yang, Hannah (Author), Lissowska, Jolanta (Author), Brinton, Louise A. (Author), Wentzensen, Nicolas (Author), Hogdall, Claus (Author), Lundvall, Lene (Author), Nedergaard, Lotte (Author), Baker, Helen (Author), Song, Honglin (Author), Eccles, Diana (Author), McNeish, Ian (Author), Paul, James (Author), Carty, Karen (Author), Siddiqui, Nadeem (Author), Glasspool, Rosalind (Author), Whittemore, Alice S. (Author), Rothstein, Joseph H. (Author), McGuire, Valerie (Author), Sieh, Weiva (Author), Ji, Bu-Tian (Author), Zheng, Wei (Author), Shu, Xiao-Ou (Author), Gao, Yu-Tang (Author), Rosen, Barry (Author), Risch, Harvey A. (Author), McLaughlin, John R. (Author), Narod, Steven A. (Author), Monteiro, Alvaro N. (Author), Chen, Ann (Author), Lin, Hui-Yi (Author), Permuth-Wey, Jenny (Author), Sellers, Thomas A. (Author), Tsai, Ya-Yu (Author), Chen, Zhihua (Author), Ziogas, Argyrios (Author), Anton-Culver, Hoda (Author), Gentry-Maharaj, Aleksandra (Author), Menon, Usha (Author), Harrington, Patricia (Author), Lee, Alice W. (Author), Wu, Anna H. (Author), Pearce, Celeste L. (Author), Coetzee, Gerry (Author), Pike, Malcolm C. (Author), Dansonka-Mieszkowska, Agnieszka (Author), Timorek, Agnieszka (Author), Rzepecka, Iwona K. (Author), Kupryjanczyk, Jolanta (Author), Freedman, Matt (Author), Noushmehr, Houtan (Author), Easton, Douglas F. (Author), Offit, Kenneth (Author), Couch, Fergus J. (Author), Gayther, Simon (Author), Pharoah, Paul P. (Author), Antoniou, Antonis C. (Author), Chenevix-Trench, Georgia (Author)
Format: Article
Language:English
Published: 2015-02.
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