Neutrophil-derived MMP-8 drives AMPK-dependent matrix destruction in Human Pulmonary Tuberculosis
Pulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix destruction resulting in cavitation is not well defined. Neutrophils are emerging as key mediators of TB immunopathology and their...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015-05-21.
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| Subjects: | |
| Online Access: | Get fulltext |