Reduced expression of the presynaptic co-chaperone cysteine string protein alpha (CSP?) does not exacerbate experimentally-induced ME7 prion disease
Infection of mice with the ME7 prion agent results in well-characterised neuropathological changes, which includes vacuolation, neurodegeneration and synaptic degeneration. Presynaptic dysfunction and degeneration is apparent through the progressive reduction in synaptic vesicle proteins and eventua...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015-03-04.
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| Subjects: | |
| Online Access: | Get fulltext |