Mechanisms of hypoxic up-regulation of versican gene expression in macrophages

Hypoxia is a hallmark of many pathological tissues. Macrophages accumulate in hypoxic sites and up-regulate a range of hypoxia-inducible genes. The matrix proteoglycan versican has been identified as one such gene, but the mechanisms responsible for hypoxic induction are not fully characterised. Her...

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Bibliographic Details
Main Authors: Sotoodehnejadnematalahi, Fattah (Author), Staples, Karl J. (Author), Chrysanthou, Elvina (Author), Pearson, Helen (Author), Ziegler-Heitbrock, Loems (Author), Burke, Bernard (Author)
Format: Article
Language:English
Published: 2015-06-09.
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