Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis

BACKGROUND: Mobile elements are active in the human genome, both in the germline and cancers, where they can mutate driver genes. RESULTS: While analysing whole genome paired-end sequencing of oesophageal adenocarcinomas to find genomic rearrangements, we identified three ways in which new mobile e...

Full description

Bibliographic Details
Main Authors: Paterson, Anna L. (Author), Weaver, Jamie M.J (Author), Eldridge, Matthew D. (Author), Tavaré, Simon (Author), Fitzgerald, Rebecca C. (Author), Edwards, Paul A.W (Author), Underwood, T.J (Author)
Format: Article
Language:English
Published: 2015-07-10.
Subjects:
Online Access:Get fulltext