Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis
BACKGROUND: Mobile elements are active in the human genome, both in the germline and cancers, where they can mutate driver genes. RESULTS: While analysing whole genome paired-end sequencing of oesophageal adenocarcinomas to find genomic rearrangements, we identified three ways in which new mobile e...
Main Authors: | Paterson, Anna L. (Author), Weaver, Jamie M.J (Author), Eldridge, Matthew D. (Author), Tavaré, Simon (Author), Fitzgerald, Rebecca C. (Author), Edwards, Paul A.W (Author), Underwood, T.J (Author) |
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Format: | Article |
Language: | English |
Published: |
2015-07-10.
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Subjects: | |
Online Access: | Get fulltext |
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