Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

OBJECTIVE: Ovarian cancer is a hormone-related disease with a strong genetic basis. However, none of its high-penetrance susceptibility genes and GWAS-identified variants to date are known to be involved in hormonal pathways. Given the hypothesized etiologic role of gonadotropins, an assessment of h...

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Main Authors: Lee, Alice W. (Author), Tyrer, Jonathan P. (Author), Doherty, Jennifer A. (Author), Stram, Douglas A. (Author), Kupryjanczyk, Jolanta (Author), Dansonka-Mieszkowska, Agnieszka (Author), Plisiecka-Halasa, Joanna (Author), Spiewankiewicz, Beata (Author), Myers, Emily J. (Author), Chenevix-Trench, Georgia (Author), Fasching, Peter A. (Author), Beckmann, Matthias W. (Author), Ekici, Arif B. (Author), Hein, Alexander (Author), Vergote, Ignace (Author), Van Nieuwenhuysen, Els (Author), Lambrechts, Diether (Author), Wicklund, Kristine G. (Author), Eilber, Ursula (Author), Wang-Gohrke, Shan (Author), Chang-Claude, Jenny (Author), Rudolph, Anja (Author), Sucheston-Campbell, Lara (Author), Odunsi, Kunle (Author), Moysich, Kirsten B. (Author), Shvetsov, Yurii B. (Author), Thompson, Pamela J. (Author), Goodman, Marc T. (Author), Wilkens, Lynne R. (Author), Dörk, Thilo (Author), Hillemanns, Peter (Author), Dürst, Matthias (Author), Runnebaum, Ingo B. (Author), Bogdanova, Natalia (Author), Pelttari, Liisa M. (Author), Nevanlinna, Heli (Author), Leminen, Arto (Author), Edwards, Robert P. (Author), Kelley, Joseph L. (Author), Harter, Philipp (Author), Schwaab, Ira (Author), Heitz, Florian (Author), du Bois, Andreas (Author), Orsulic, Sandra (Author), Lester, Jenny (Author), Walsh, Christine (Author), Karlan, Beth Y. (Author), Hogdall, Estrid (Author), Kjaer, Susanne K. (Author), Jensen, Allan (Author), Vierkant, Robert A. (Author), Cunningham, Julie M. (Author), Goode, Ellen L. (Author), Fridley, Brooke L. (Author), Southey, Melissa C. (Author), Giles, Graham G. (Author), Bruinsma, Fiona (Author), Wu, Xifeng (Author), Hildebrandt, Michelle A.T (Author), Lu, Karen (Author), Liang, Dong (Author), Bisogna, Maria (Author), Levine, Douglas A. (Author), Weber, Rachel Palmieri (Author), Schildkraut, Joellen M. (Author), Iversen, Edwin S. (Author), Berchuck, Andrew (Author), Terry, Kathryn L. (Author), Cramer, Daniel W. (Author), Tworoger, Shelley S. (Author), Poole, Elizabeth M. (Author), Olson, Sara H. (Author), Orlow, Irene (Author), Bandera, Elisa V. (Author), Bjorge, Line (Author), Tangen, Ingvild L. (Author), Salvesen, Helga B. (Author), Krakstad, Camilla (Author), Massuger, Leon F.A.G (Author), Kiemeney, Lambertus A. (Author), Aben, Katja K.H (Author), van Altena, Anne M. (Author), Bean, Yukie (Author), Pejovic, Tanja (Author), Kellar, Melissa (Author), Le, Nhu D. (Author), Cook, Linda S. (Author), Kelemen, Linda E. (Author), Brooks-Wilson, Angela (Author), Lubinski, Jan (Author), Gronwald, Jacek (Author), Cybulski, Cezary (Author), Jakubowska, Anna (Author), Wentzensen, Nicolas (Author), Brinton, Louise A. (Author), Lissowska, Jolanta (Author), Yang, Hannah (Author), Nedergaard, Lotte (Author), Lundvall, Lene (Author), Hogdall, Claus (Author), Song, Honglin (Author), Campbell, Ian G. (Author), Eccles, Diana (Author), Glasspool, Rosalind (Author), Siddiqui, Nadeem (Author), Carty, Karen (Author), Paul, James (Author), McNeish, Iain A. (Author), Sieh, Weiva (Author), McGuire, Valerie (Author), Rothstein, Joseph H. (Author), Whittemore, Alice S. (Author), McLaughlin, John R. (Author), Risch, Harvey A. (Author), Phelan, Catherine M. (Author), Anton-Culver, Hoda (Author), Ziogas, Argyrios (Author), Menon, Usha (Author), Ramus, Susan J. (Author), Gentry-Maharaj, Aleksandra (Author), Harrington, Patricia (Author), Pike, Malcolm C. (Author), Modugno, Francesmary (Author), Rossing, Mary Anne (Author), Ness, Roberta B. (Author), Pharoah, Paul D.P (Author), Stram, Daniel O. (Author), Wu, Anna H. (Author), Pearce, Celeste Leigh (Author)
Format: Article
Language:English
Published: 2015-03.
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