Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovarian cancer risk according to histological subtype. Here we com...

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Main Authors: Shen, Hui (Author), Fridley, Brooke L. (Author), Song, Honglin (Author), Lawrenson, Kate (Author), Cunningham, Julie M. (Author), Ramus, Susan J. (Author), Cicek, Mine S. (Author), Tyrer, Jonathan (Author), Stram, Douglas (Author), Larson, Melissa C. (Author), Köbel, Martin (Author), Ziogas, Argyrios (Author), Zheng, Wei (Author), Yang, Hannah P. (Author), Wu, Anna H. (Author), Wozniak, Eva L. (Author), Ling Woo, Yin (Author), Winterhoff, Boris (Author), Wik, Elisabeth (Author), Whittemore, Alice S. (Author), Wentzensen, Nicolas (Author), Palmieri Weber, Rachel (Author), Vitonis, Allison F. (Author), Vincent, Daniel (Author), Vierkant, Robert A. (Author), Vergote, Ignace (Author), Van Den Berg, David (Author), Van Altena, Anne M. (Author), Tworoger, Shelley S. (Author), Thompson, Pamela J. (Author), Tessier, Daniel C. (Author), Terry, Kathryn L. (Author), Teo, Soo-Hwang (Author), Templeman, Claire (Author), Stram, Daniel O. (Author), Southey, Melissa C. (Author), Sieh, Weiva (Author), Siddiqui, Nadeem (Author), Shvetsov, Yurii B. (Author), Shu, Xiao-Ou (Author), Shridhar, Viji (Author), Wang-Gohrke, Shan (Author), Severi, Gianluca (Author), Schwaab, Ira (Author), Salvesen, Helga B. (Author), Rzepecka, Iwona K. (Author), Runnebaum, Ingo B. (Author), Anne Rossing, Mary (Author), Rodriguez-Rodriguez, Lorna (Author), Risch, Harvey A. (Author), Renner, Stefan P. (Author), Poole, Elizabeth M. (Author), Pike, Malcolm C. (Author), Phelan, Catherine M. (Author), Pelttari, Liisa M. (Author), Pejovic, Tanja (Author), Paul, James (Author), Orlow, Irene (Author), Zawiah Omar, Siti (Author), Olson, Sara H. (Author), Odunsi, Kunle (Author), Nickels, Stefan (Author), Nevanlinna, Heli (Author), Ness, Roberta B. (Author), Narod, Steven A. (Author), Nakanishi, Toru (Author), Moysich, Kirsten B. (Author), Monteiro, Alvaro N.A (Author), Moes-Sosnowska, Joanna (Author), Modugno, Francesmary (Author), Menon, Usha (Author), McLaughlin, John R. (Author), McGuire, Valerie (Author), Matsuo, Keitaro (Author), Mat Adenan, Noor Azmi (Author), Massuger, Leon F.A.G (Author), Lurie, Galina (Author), Lundvall, Lene (Author), Lubiński, Jan (Author), Lissowska, Jolanta (Author), Levine, Douglas A. (Author), Leminen, Arto (Author), Lee, Alice W. (Author), Le, Nhu D. (Author), Lambrechts, Sandrina (Author), Lambrechts, Diether (Author), Kupryjanczyk, Jolanta (Author), Krakstad, Camilla (Author), Konecny, Gottfried E. (Author), Krüger Kjaer, Susanne (Author), Kiemeney, Lambertus A. (Author), Kelemen, Linda E. (Author), Keeney, Gary L. (Author), Karlan, Beth Y. (Author), Karevan, Rod (Author), Kalli, Kimberly R. (Author), Kajiyama, Hiroaki (Author), Ji, Bu-Tian (Author), Jensen, Allan (Author), Jakubowska, Anna (Author), Iversen, Edwin (Author), Hosono, Satoyo (Author), Høgdall, Claus K. (Author), Høgdall, Estrid (Author), Hoatlin, Maureen (Author), Hillemanns, Peter (Author), Heitz, Florian (Author), Hein, Rebecca (Author), Harter, Philipp (Author), Halle, Mari K. (Author), Hall, Per (Author), Gronwald, Jacek (Author), Gore, Martin (Author), Goodman, Marc T. (Author), Giles, Graham G. (Author), Gentry-Maharaj, Aleksandra (Author), Garcia-Closas, Montserrat (Author), Flanagan, James M. (Author), Fasching, Peter A. (Author), Ekici, Arif B. (Author), Edwards, Robert (Author), Eccles, Diana (Author), Easton, Douglas F. (Author), Dürst, Matthias (Author), du Bois, Andreas (Author), Dörk, Thilo (Author), Doherty, Jennifer A. (Author), Despierre, Evelyn (Author), Dansonka-Mieszkowska, Agnieszka (Author), Cybulski, Cezary (Author), Cramer, Daniel W. (Author), Cook, Linda S. (Author), Chen, Xiaoqing (Author), Charbonneau, Bridget (Author), Chang-Claude, Jenny (Author), Campbell, Ian (Author), Butzow, Ralf (Author), Bunker, Clareann H. (Author), Brueggmann, Doerthe (Author), Brown, Robert (Author), Brooks-Wilson, Angela (Author), Brinton, Louise A. (Author), Bogdanova, Natalia (Author), Block, Matthew S. (Author), Benjamin, Elizabeth (Author), Beesley, Jonathan (Author), Beckmann, Matthias W. (Author), Bandera, Elisa V. (Author), Baglietto, Laura (Author), Bacot, François (Author), Armasu, Sebastian M. (Author), Antonenkova, Natalia (Author), Anton-Culver, Hoda (Author), Aben, Katja K. (Author), Liang, Dong (Author), Wu, Xifeng (Author), Lu, Karen (Author), Hildebrandt, Michelle A.T (Author), Schildkraut, Joellen M. (Author), Sellers, Thomas A. (Author), Huntsman, David (Author), Berchuck, Andrew (Author), Chenevix-Trench, Georgia (Author), Gayther, Simon A. (Author), Pharoah, Paul D.P (Author), Laird, Peter W. (Author), Goode, Ellen L. (Author), Leigh Pearce, Celeste (Author)
Format: Article
Language:English
Published: 2013-03-27.
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