Polyunsaturated fatty acid biosynthesis is involved in phenylephrine-mediated calcium release in vascular smooth muscle cells

Stimulation of vascular smooth muscle (VSM) ?1-adrenoceptors induces myosin phosphorylation and vasoconstriction via mobilisation of intracellular calcium and production of specific eicosanoids. Polyunsaturated fatty acid (PUFA) biosynthesis in VSM cells is involved, although the precise mechanism i...

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Bibliographic Details
Main Authors: Irvine, Nicola A. (Author), Lillycrop, Karen A. (Author), Fielding, Barbara (Author), Torrens, Christopher (Author), Hanson, Mark A. (Author), Burdge, Graham C. (Author)
Format: Article
Language:English
Published: 2015-10.
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