Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis

Objective To determine whether altered IL8 methylation status is associated with increased expression of IL8 in human osteoarthritic (OA) chondrocytes. Methods IL8 expression levels and the percentage CpG methylation in human chondrocytes were quantified by qRT-PCR and pyrosequencing in OA patien...

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Bibliographic Details
Main Authors: Takahashi, A. (Author), de Andrés, M.C (Author), Hashimoto, K. (Author), Itoi, E. (Author), Oreffo, R.O.C (Author)
Format: Article
Language:English
Published: 2015.
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