Dysregulation of anti-viral function of CD8+T cells in the COPD lung: role of the PD1/PDL1 axis

Rationale: COPD patients are susceptible to respiratory viral infections which cause exacerbations. Mechanisms underlying susceptibility are not understood. Effectors of the adaptive immune response; CD8+ T cells which clear viral infections, are present in increased numbers in lungs of COPD patient...

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Main Authors: McKendry, Richard T. (Author), Spalluto, C. Mirella (Author), Burke, Hannah (Author), Nicholas, Ben (Author), Cellura, Doriana (Author), Al-Shamkhani, Aymen (Author), Staples, Karl J. (Author), Wilkinson, Tom M.A (Author)
Format: Article
Language:English
Published: 2016-03-15.
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